What is GHRP-2?
Growth hormone releasing peptide-2. Research compound.
GHRP-2 is a synthetic GH secretagogue that strongly stimulates growth hormone release. It also increases cortisol and prolactin more than some alternatives. Research compound not approved for human use.
What the evidence says
The overall evidence grade for GHRP-2 is C (limited — early or preliminary data, mostly mechanistic or animal). Research compound. Some clinical data but not FDA approved.
Specific findings with supporting evidence:
- Potently stimulates GH release. Evidence grade B.
- Increases cortisol and prolactin. Evidence grade B.
Best-supported outcomes:
- Research interest only.
Where marketing outpaces evidence:
- The claim that "FDA approved" is not supported by the evidence (grade A).
- Marketing often overstates: Best GH peptide.
- Marketing often overstates: No hormonal side effects.
Dose and timing
Take it in the evening on an empty stomach. Research compound only.
Who it's for, and who should skip it
Most relevant for:
- Research interest only.
Not appropriate for:
- Anyone without medical supervision.
Safety and cautions
Important: Not FDA approved. Research compound. Caution: Hormonal effects. Affects cortisol and prolactin.
Common mistakes
- Ignoring hormonal side effects.
- Self-administration.
Myths vs reality
A common misconception: GHRP-2 only affects growth hormone. In reality, it also increases cortisol and prolactin.
How it interacts with other compounds
- GHRP-2 works well alongside ghrp 6 — same peptide family.
- GHRP-2 works well alongside ipamorelin — both GH secretagogues.
Questions people ask
How does GHRP-2 compare to ipamorelin? GHRP-2 is more potent but less selective, affecting more hormones.
Editorial note
This guide summarizes the published evidence on GHRP-2. It is educational content, not medical advice. Confirm with your clinician if you take prescription medications or manage a chronic condition.